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Use of OpenRouter’s Responses API (Beta) to access OpenAI-compatible models across multiple providers.

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Prerequisites

Set OPENROUTER_API_KEY environment variable. 

import asyncio

from agno.agent import Agent
from agno.models.openrouter import OpenRouterResponses

# ---------------------------------------------------------------------------
# Create Agent
# ---------------------------------------------------------------------------

agent = Agent(
    model=OpenRouterResponses(id="openai/gpt-oss-20b", reasoning={"enabled": True}),
    markdown=True,
)

# Print the response in the terminal

# ---------------------------------------------------------------------------
# Run Agent
# ---------------------------------------------------------------------------
if __name__ == "__main__":
    # --- Sync ---
    agent.print_response("Share a 2 sentence horror story")

    # --- Async ---
    asyncio.run(agent.aprint_response("Share a 2 sentence horror story"))

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Run the Example

# Clone and setup repo
git clone https://github.com/agno-agi/agno.git
cd agno/cookbook/90_models/openrouter/responses

# Create and activate virtual environment
./scripts/demo_setup.sh
source .venvs/demo/bin/activate

# Export relevant API keys
export OPENROUTER_API_KEY="***"

python basic.py